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Interestingly, when ghrelin is administered alone to cells coexpressing D1R and GHSR1a, no increase in cAMP accumulation is observed, while typical levels of Ca 2+ accumulation associated with GHSR1a activation occur (Jiang et al., 2006)

doi: 10.1016/j.gde.2006.12.007

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J Control Release 367:402424 [DOI] [PubMed] [Google Scholar] 28.McCollum L, Karlawish J (2020) Cognitive impairment evaluation and management