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TIGAR protein is mainly found in the endoplasmic reticulum, cytoplasm, matrix and mitochondrial membrane of brain tissues (Geng et al., 2018)

Reduced testosterone in men can produce decreased libido, weaker erections, and fatigue, while estrogen-progesterone imbalances in women may cause diminished libido, vaginal dryness, and mood variations

doi: 10.1517/13543784.2013.825249

Discovery and Engineering of Enhanced SUMO Protease Enzymes
