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Marked elevation in plasma trimethylamine-N-oxide (TMAO) in patients with mitochondrial disorders treated with oral l-carnitine

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Mice prone to neurodegeneration were treated with DMB, which increased memory, decreased amyloid aggregation, and decreased inflammation

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103 In one randomized clinical trial in 70 volunteers with chronic tinnitus, both 3 mg of melatonin daily and a standard dose of sertraline (Zoloft) (an antidepressant medication) for three months reduced tinnitus severity, but melatonin was more effective
