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In particular, there is unquestionably a strong correlation between sleep disturbances and arterial hypertension, cardiovascular illness, diabetes mellitus, and/or obesity, according to observational research and experimental data (the Italian Society of Hypertension (SIIA) et al., 2021) and sleep disorders do have a significant impact on hypertensive patients and also the main cardiovascular consequences linked to hypertension include myocardial infarction, heart failure, stroke, and death
Diabetologia 63(12):2605-15 2020 PMC7641942 Vehik K, Bonifacio E, Lernmark A, Yu L, Williams A, Schatz D, Rewers M, She JX, Toppari J, Hagopian WA, Akolkar B, Ziegler AG, Krischer JP, TEDDY Study Group

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At Risk Patients [1,2] Hyperammonemic encephalopathy may occur at any time during therapy with valproic acid
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