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All of these receptors are single polypeptides that span the membrane seven times (See Fig

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Emerging evidence also implicates gutbrain axis dysfunction and microbiome dysbiosis in PD, where peripheral synuclein pathology and intestinal inflammation may propagate neurodegeneration via vagal pathways [26]

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PNC-27 was not shown to have any significant effects on cell viability of normal murine lymphocytes, however, the peptide was capable of selectively targeting human leukemia cells without affecting normal lymphoid control cells