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Furthermore, the study hypothesizes a potential interaction of AOD9604 with the beta-adrenergic pathway, especially concerning the beta(3)-adrenergic receptors (beta(3)-AR), which are considered to be key lipolytic receptors found in fat cells

During phase I, the subjects begin forcefully exhalating against a closed airway, the intrathoracic pressure suddenly increases which leads to the brief increase in the systemic arterial blood pressure (ABP) and cerebral bloof flow

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These processes may trigger inflammatory reactions, ultimately leading to the occurrence of arrhythmia