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In animal models, supplementation prevented synaptic damage induced by chronic alcohol, according to a study by Shi Z et al

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[DOI] [PMC free article] [PubMed] [Google Scholar] Fritz KS, Galligan JJ, Hirschey MD, et al

TAAR1 activation initiates signaling cascades involving cyclic AMP (cAMP), protein kinase A (PKA), protein kinase C (PKC), and calcium/calmodulin-dependent protein kinase II alpha (CAMKII)