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A new water soluble MAPK activator exerts antitumor activity in melanoma cells resistant to the BRAF inhibitor vemurafenib

This dual action, building while reducing breakdown, shifts the collagen balance decisively toward net accumulation

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Through the Leloir pathway , it can be converted into glucose 1-phosphate, which in turn can be isomerized to glucose 6-phosphate

How Supplied Pemetrexed for injection, USP is a white-to-light yellow or green-yellow lyophilized powder supplied in single-dose vials for reconstitution for intravenous infusion