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After 1 h of co-incubation on ice at pH 6.5, most AsiG co-localized with the tumor cell membrane along with some red fluorescence dispersing in the cytoplasm, suggesting the aptamer-facilitated cell-targeting and cellular uptake of siG

CKD, chronic kidney disease

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Ongoing trials and regulatory developments in MASLD Significant advances have been made in the clinical development pipeline for MASLD, with several therapeutic agents progressing to late-stage trials and achieving key regulatory milestones