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PMCID: PMC7824176

Anti-CD38 Antibodies Anti-CD38 monoclonal antibodies are shown to be highly efficacious in the treatment of multiple myeloma (MM) and pre-clinical studies highlight the potential use in other tumors such as CLL, lung cancer, prostate cancer and melanoma (29, 70, 7274, 76, 9599) and in a preclinical model of melanoma (87)

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In response to physical exercise, the body produces hepcidin , a hormone responsible for regulating iron metabolism

While efficacy endpoints for weight loss in those trials were modest, the compound exhibited a favorable safety profile, supporting its later GRAS designation for food use