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These findings confirm that HA handling is highly involved in renal water metabolism under the influence of AVP, which could play a key role in BP regulation under both physiological and water-load conditions by alternatively targeting hyaluronidase activity and the AQP2 channel system

The viral hijack of human ACE2 receptor disrupts RAAS activation, upregulates NF-B pathway and the ensuing cytokine storm, hypertension, cell proliferation, inflammation, and fibrosis elicits detrimental effects on every bodily organ, the CV system, in particular 635

Theranostics 13 (14), 49935016
Merrill AH, Sullards MC, Wang E et al (2001) Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins

Initial treatment for B12 deficiency with neurological involvement: When elderly patients present with neurological symptoms (peripheral neuropathy, cognitive impairment, subacute combined degeneration of the cord), urgent and aggressive replacement is essential to prevent irreversible damage
