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The retina has enzymatic mechanisms for scavenging of free radicals as well as intrinsic antioxidant and redox systems for dealing with other types of ROS 17

142 The action of ASP was also evaluated in vitro, providing novel evidence for its growth inhibitory effect, antiproliferative, proapoptotic, and antifibrotic actions on cultured leiomyoma cells in the absence of comparable effects on cultured normal myometrial cells

Before establishing the SSRP Institute and Redox Medical Group, Dr

10.1016/j.ejphar.2022.174797 76 HangauerM

However, excessive NFE2L2 activation may also promote intracellular cysteine accumulation, which can react with sugars to form adducts that impair cell proliferation 163