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To safely take Vitamin B12 and folic acid together, patients should: Ask their oncologist before starting any supplements Tell their doctor about all current meds and supplements Stick to the recommended doses By working with their healthcare team, cancer patients can make smart choices about supplements

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Several practical unknowns compound this

PMID 16953016

Additionally, some studies investigate whether vitamin b12 on empty stomach supplementation has advantages, prompting questions like "Can you take vitamin b12 on an empty stomach to maximize absorption?" New research: Enhanced vitamin B12 absorption on an empty stomach A recent study, "Comparative Absorption of Vitamin B12 in Fasting and Fed States: Implications for Supplementation Practices," published in January 2025 in the Journal of Nutritional Science , examined the absorption rates of vitamin B12 when taken on an empty stomach versus with food