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Cambridge, UK: Cambridge University Press

doi: 10.1016/j.cmet.2017.04.015

The antidepressant response to LAC occurs after 3 days of administration and lasts for at least 14 days, whereas the action of standard antidepressant drugs (fluoxetine and clomipramine) requires 14 days of consecutive administration and disappears after drug withdrawal in the same rodent models [30, 34]
2018;15(7):e1002615

In appropriate patients, it may also contribute to broader cardiometabolic benefits, such as improved weight, better glycaemic control, and support for overall risk reduction as part of a clinician-led treatment plan
