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Ice crystal formation during freezing physically damages the peptide structure in solution

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GHK-Cu exhibits some potential to influence various biological pathways, including an apparent induction of tissue repair, attraction of immune cells, antioxidant and anti-inflammatory characteristics, activation of collagen and glycosaminoglycan synthesis in skin fibroblasts, regulation of extracellular matrix components like decorin, and possible promotion of blood vessel growth

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Platelets are closely associated with regulating pro-angiogenic factors, such as vascular endothelial growth factor (VEGF), angiopoietin 1, etc
