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doi: 10.1093/hmg/11.9.1137

Persistent SASP signaling contributes to local tissue dysfunction and chronic inflammatory microenvironments in aging models

Fatigue exacerbates these issues by impairing muscle function and coordination

They demonstrated that electrophoresis of purified myofibrils treated with cathepsin L resulted in patterns which were almost identical to patterns of proteins recovered from muscle from spawning fish

In general, this effect could be reversed by folate administration [117]
