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[DOI] [PMC free article] [PubMed] [Google Scholar] 195.Neschen S, Morino K, Hammond LE, Zhang D, Liu ZX, Romanelli AJ, et al

Shaking creates foam and mechanical stress that breaks peptide chains

excess is renally excreted, though very high levels can cause dermatologic or metabolic effects

No serious adverse events were attributed to AOD-9604 across the entire clinical trial program involving over 900 participants
