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Furthermore, OXPHOS in tumor cells was also suppressed due to the absence of alternative fuels as carbon sources for the TCA cycle [114]
10.1016/j.neuint.2012.12.005 Neurochem

People with moderate to severe thalassemia may need blood transfusions every 4 months

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Application of the MCU inhibitor Ru360 can prevent mitochondrial calcium overload and block ROS production, thereby ameliorating iron overload-induced mitochondrial dysfunction in mouse brains [52]
