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An additional limitation of these studies is that they cannot directly examine specific biological pathways

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(EC 2.3.1.137) Specifically, CROT catalyzes the chemical reaction: octanoyl-CoA + L-carnitine CoA + L-octanoylcarnitine Thus, the two substrates of this enzyme are octanoyl-CoA and L-carnitine and its two products are CoA and L-octanoylcarnitine

Notably, absorption of L-carnitine in foods containing L-carnitine is much higher (54% to 87%) than from dietary supplements, where absorption is only about 15% [69]