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Particularly, the cryo-EM structures of polymerases from filovirus and human metapneumovirus have no densities for the accessory regions in their L proteins even if the full-length L proteins are used for sample preparation and structural determination 8,9,32,33,34,35 , whereas the accessory regions attached to the core region can be observed in the structures of paramyxoviral and rhabdoviral polymerases 3,26,27,28,29,30,31

The suprachiasmatic nucleus synchronizes growth hormone secretory rhythms with the light-dark cycle

1 Challenges in Peptide Sequencing Peptide bond identification While MS/MS fragmentation is effective, achieving complete fragmentation across every peptide bond (full b- and y-ion series) is rare

Gauge refers to the thickness of the needle (the diameter)