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Currently the evidence is non-existent as to whether they inhibit/downregulate MRP1 in the brush border enterocytes

Due to the high intracellular concentrations of GSH (110 mM) in aerobic organisms, GSH biosynthesis pathways must function efficiently to maintain adequate levels of this important low molecular-weight thiol

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[DOI] [PubMed] [Google Scholar] 128.Pasupathy S., Tavella R., Grover S., Raman B., Procter N.E.K., Du Y.T., Mahadavan G., Stafford I., Heresztyn T., Holmes A., et al