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Roth J, et al

Muscle is a central endocrine mediator, particularly due to the production of myokines (i.e., myostatin, -aminoisobutyric acid, IL-15, irisin, meteorin-like and myonectin), which are critical mediators of the crosstalk between muscle and other tissues and organs to regulate metabolic homeostasis [166]

In vivo yeast assays demonstrated that ChaC1 and its homologues promote growth on GSH by breaking it down into 5-oxoproline and cys-gly, a function lost in catalytic mutants

As seen in the figure, all these components eluted from the column in the form of a single symmetrical peak

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Xu Z., Elrashidy R.A., Li B., Liu G