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Only one study (172) observed negative correlations of serum and seminal plasma Se levels with sperm count and viability, respectively, but still a positive correlation of seminal plasma Se levels with sperm motility, while two studies observed no correlation (194, 195)

[DOI] [PMC free article] [PubMed] [Google Scholar] 54.Anderson C.M., Stahl A

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Studies in rams showed that Se supplementation increased testosterone levels, sperm motility, volume, and concentration, decreased the percentage of abnormal sperm, dead sperm, or sperm with acrosome damage, and increased scrotal circumference (183)

In addition, selenoprotein P mRNA was also expressed in rat Leydig cells, and its expression was stimulated during steroidogenesis (170), indicating the possible role in the antioxidant defense against increased ROS production during steroidogenesis (100)
