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Inadequate protein during a caloric deficit leads to muscle loss rather than fat loss, defeats the purpose of the protocol, and creates the metabolic slowdown that causes weight loss plateaus

Lpez-Ojeda W, Hurley RA (2025) New trends in peptide therapies: perspectives and implications for clinical neurosciences

Symptom management : Specific symptoms of Hashimotos disease, such as fatigue, dry skin, and muscle aches, can be managed

Potential limitations of both studies include the use of a single dose rather than multiple doses of cagrilintide and the use of doses (0.6 mg in the renal impairment study and 0.9 mg in the hepatic impairment study) lower than the 2.4 mg dose being evaluated in clinical development

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