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It has been shown that UCB causes oxidative stress, p38MAPK, and GSH depletion activation in splenocytes, among other internal and extrinsic pathways

[DOI] [PubMed] [Google Scholar] 451.Bhattacharya D., Saha A., Mandal P.C

doi: 10.1046/j.1471-4159.1998.71010078.x

In the cochlea, all three members of Dvls have been implicated to mediate the Wnt/PCP pathway (Figure 3)

And CDR three is when we begin rebuilding the communication lines between different body systems
