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[DOI] [PubMed] [Google Scholar] 28.Qin L, Bartlett H, Griffiths HR, Eperjesi F, Armstrong RA, Gherghel D

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These approaches include the combined use of STING agonists, Nrf2 inhibitors, lactate metabolism blockers, and mitoNIDs, which collectively alleviate immunosuppressive metabolic states, restore T cell function [89,90,91], and improve the responsiveness of MSS CRC to immune ICIs