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Within the framework of clinical trial design, predictive modeling based on imaging, body fluid biomarkers, genetics, and digital signals can enhance participant selection, identify fast progressors or treatment-responsive subgroups, and enable real-time adaptive modifications to trial parameters

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[DOI] [PubMed] [Google Scholar] 21.Stipanuk M.H., Dominy J.E., Jr., Lee J.I., Coloso R.M