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Description
-Linolenic acid (18:3n-3) Although flaxseed oil is generally well tolerated, high doses may cause loose stools or diarrhea (211)
Key limitation: The intranasal route for bremelanotide was ultimately not pursued for regulatory approval due to the combination of lower and more variable bioavailability, higher incidence of blood pressure elevation, and less predictable pharmacokinetics compared with the subcutaneous route (reported in studies) [10] [17]
Glass R, Hope VD, Njoroge J, Edmundson C, Smith J, McVeigh J, et al
PT-141 can raise systolic blood pressure by somewhere around 6 to 12 points for a period of time
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