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Cells lacking PINK1 exhibit a stronger response to iron overload, and the mRNA levels of the iron storage proteins FTH1 and FTL1 are significantly increased, indicating that the iron metabolic response is altered (197)

An imbalance in the ratio between reduced (GSH) and oxidised (GSSG) forms of glutathione is implicated in various enterovirus infections 23 and depletion of cellular GSH levels using the GSH biosynthesis inhibitor L-buthionine sulfoximine (BSO) 24,25 and the small molecule inhibitor TP219 26 blocks the assembly and morphogenesis of many enterovirus capsids

Pan-cancer analysis of intra-tumor heterogeneity in 9,116 cancers using a novel regularized likelihood model

Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children

It is involved in nutrient assimilation, regulating immune response, and protecting against oxidative stress