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The PKR mRNA encodes the larger of the two PK isoforms which is a 574 amino acid protein
Consistent with the human genetic study, PGRN deficiency has been shown to exacerbate Gaucher disease-associated phenotypes of Gba1 D409V/D409V knockin mice [214]
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doi: 10.1093/humrep/dev031
[PubMed] [Google Scholar] 591
