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In addition to lipids, proteins are also susceptible to oxidative modifications due to ROS and reactive nitrogen species (RNS)

However, when the energy expended during exercise is derived from lipids, a large amount of energy can be continuously supplied via aerobic metabolism

doi: 10.1186/s13578-023-01053-z 97 CaiWHaddadMHaddadRKestenIHoffmanTLaanRet al
These effects are generally not a reason to stop therapy

Amyloid in neurodegenerative diseases: friend or foe
