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Studies show that only 1-5% of oral B12 actually reaches your bloodstream, particularly in individuals with absorption issues
doi: 10.1111/j.1432-1033.1980.tb04605.x
19 AST controls the NAD+/NADH ratio in cells by taking part in the malate-aspartate shuttle in which NADH is oxidized

Chem Eng J 462:142338

Amphetamine-type central nervous system stimulants release norepinephrine more potently than they release dopamine and serotonin
