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Inhibitory effects of IPSC-MSCS and their extracellular vesicles on the onset of sialadenitis in a mouse model of Sjogrens syndrome

The visceral fat deposition was also found to be reduced, along with decreased plaque macrophages and smaller aortic plaques [56]

This multi-pronged approach distinguishes it as a particularly robust immunomodulatory agent

The detailed elucidation of these multiple ROS sourcesmitochondria, NADPH oxidase, xanthine oxidase, and CYP450 enzymesreveals that oxidative stress in PCOS is a complex, multi-factorial burden, not attributable to a single pathway

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