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Non-specific symptoms and signs are loss of appetite, diarrhoea, fatigue and weakness, shortness of breath, low blood pressure, confusion, and change in mental states.9 29 Classical manifestations include Hunters glossitis, megaloblastic anaemia, and subacute combined degeneration of spinal cord (Table 29)

Results of curve fitting and threshold effect analysis After excluding participants with vitamin B12 1,000 pg/mL ( n = 15), a significant threshold effect was observed at 358.7 pg/mL

JNK, c-Jun N-terminal kinase

Hycomin injection is an injectable product that contains high levels of Hydroxocobalamin, also known as Vitamin B-12

96 - 101 exhibits high safety (LD1 not achieved)