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DNA methylation is characterized by the presence of methyl groups (CH 3 ) at DNA cytosines, primarily in the cytosineguanine (CpG) context [9]

Nogueira et al., 2008), the efficient detoxification of ROS is a requisite for cell proliferation

Any researcher working with this compound should treat the animal-to-human gap as the central open question

Accumulated free iron provides abundant substrate for this reaction, as the iron reacts with hydrogen peroxide to produce highly reactive ROS

Presently, the plethora of identified NRF2 activators is of electrophilic nature and targets the reactive cysteine residues of KEAP1