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When intracellular copper levels increase, it can promote the activity of ULK1 and ULK2 kinases, thereby increasing autophagy flux and promoting the growth and survival of lung tumor cells (88)

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We need to do careful long-term studies to evaluate how well tesofensine can help keep off weight, look at its safety over time, and check for any late side effects

287 , H2768H2776 (2004)
