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The chemistry of reactive oxygen species (ROS) revisited: outlining their role in biological macromolecules (DNA, lipids and proteins) and induced pathologies

As per the latest diagnostic criteria, MetS necessitates the presence of any three out of the following five conditions: elevated fasting glucose or type 2 diabetes (T2D), hypertriglyceridemia, lowered high-density lipoprotein (HDL) cholesterol levels, central obesity, or hypertension (Tilg et al., 2020)

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Exercise programming: Resistance training 3-5x weekly to maintain muscle mass during fat loss, moderate-intensity cardiovascular activity to enhance fat oxidation, and potentially fasted morning cardio to leverage elevated free fatty acids from AOD-9604 administration