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Sulforaphane upregulates the heat shock protein co-chaperone chip and clears amyloid- and tau in a mouse model of Alzheimer's disease

Of particular note is the presence of the protein HNRNPA1 (Heterogeneous nuclear ribonucleoprotein A1) in the network, a key RNA-binding protein that regulates the alternative splicing of PKM pre-mRNA, thereby favoring the formation of PKM2 mRNA over that of PKM1 41,42

Many researchers have attempted to prolong the acting time of exenatide by preparing sustained-release dosage forms, modifying its structure, gene therapies, and other means

[DOI] [PubMed] [Google Scholar] 93.Maddocks ODK, et al

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