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3.4.3 Mechanistic insights from preclinical modelsbarrier, immune, and neurotransmitter changes Rodent models of PTSD provide causal evidence that psychological trauma disrupts the MGBA, leading to microbiota alterations, compromised gut barrier integrity, immune activation and neurotransmitter imbalance

10.1016/j.semcancer.2022.06.014 142 NaseerF

In mammals, they are classified based on their roles in apoptotic regulation into initiator caspases, such as caspase-1, -2, -4, -5, -8, -9, -10, -11, and -12

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We listen because gut issues are often dismissed or oversimplified, and by the time patients reach us, theyve usually been through years of frustration