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(80) conducted an epigenome-wide association study of TCE-exposed workers and found variability in the blood DNA methylation profile, such that human exposure to TCE was associated with epigenetic alterations in genes involved in cell matrix adhesions and interferon subtype expression, which are important in the development of autoimmune diseases, and in genes related to cancer development

On the other hand, it must be stressed that the above values are averages and there might be significant spatial heterogeneity 57

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Targeting ferroptosis offers a novel therapeutic strategy and insight for the treating platinum-tolerant cancer cells and potentially persistent cancer cells