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The pretraining comprised of four sessions on three successive days adopting an accelerating protocol that began at 5 rpm and increased to 20 rpm in 5 min

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Additionally, Kong et al [41] showed that dietary factors metabolised by gut microbes can produce trimethylamine, which is transported to the liver and converted by hepatic flavin mono-oxygenase 3 (FMO3) into trimethylamine N -oxide (TMAO)

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