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It eliminates the body's free radicals

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The activation of TFEB requires modification of a specific lysine residue in the translation initiation factor 5A (eIF-5A) generating what is called hypusine (derived from hy droxy pu trescine and ly sine ) which involves spermidine as outlined in the Polyamines in Protein Modification below

S2CID 35209784

5 Clinical evidence and limitations 5.1 Selenium in thyroid populations Selenium has been one of the most intensively studied micronutrients in thyroid disease, with multiple randomized controlled trials (RCTs) examining its effects in Hashimoto's thyroiditis and other autoimmune conditions