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Signs of dehydration include thirst, less-frequent urination, dark-colored urine, dry mouth, feeling tired, sunken eyes or cheeks, light-headedness or fainting, and decreased skin turgor (when the skin is pinched and released, it does not flatten back to normal right away)

Despite extensive research, current therapeutic options provide only symptomatic relief and fail to halt or reverse disease progression, highlighting the urgent need for novel and effective treatment strategies

Loss of the epithelial marker E-cadherin may impair cell-cell adhesion, cell-matrix adhesion, and cell polarity

J Gen Physiol

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