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While this investigation was not specifically focused on AD, the observed anti-inflammatory and neuroprotective effects suggest that YSTJ may hold therapeutic potential for Alzheimers disease
84 Epigenetic alterations such as histone modifications (e.g., H3K9me3 loss) contribute to the upregulation of inflammatory genes and an imbalance in macrophage polarization, further reinforcing systemic inflammation
doi: 10.1016/j.redox.2020.101674 86 OkoyeCNKorenSAWojtovichAP
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We also acknowledge the collaboration of Indiana Blood Center and Daniel Smith of Transfusion Medicine at Indiana University
