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Further gene expression analyses revealed that at the transcriptional level, knocking down individual SAA enzymes has distinct impacts on EMT changes that are induced by HNF4 deficiency (Fig

Among these, the NOD-, LRR-, and pyrin domain-containing 3 (NLRP3) inflammasome plays a significant role in APAP-induced liver injury

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Nevertheless, not all the trials possessed the essential prerequisites to confirm the true potential of this approach