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This is thought to be due to anaemia that can occur as a result of vitamin b12 deficiency

Unnatl Amino Acids Methods Protoc 794:135167

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183 In addition, Small molecule antagonists which inhibit TGF- receptor kinase or TGF- activated pathways were studied, 184,185 although the long-term safety of such drugs might be a problem, particularly as TGF- affects tissue repair and is a potent anti-inflammatory mediator (Table 3)
