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Furthermore, animal studies demonstrated that 12-day consecutive topical application of both (GA + Lico-A) micelles and Lico-A significantly attenuated UVB-induced hyperpigmentation in murine models, within MAPK/ERK pathway distribution patterns correlating precisely with areas of decreased tyrosinase activity (Wang et al., 2025)

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With respect to brain tumors, strategies that transiently open the blood brain barrier to enable delivery of drugs are of considerable interest [334]

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