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Ecotoxicol Environ Saf 128:206212

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In mild to moderate cases, treatment mainly includes topical anti-psoriatic agents, i.e., topical steroids, topical calcineurin inhibitors, vitamin D analogs, and retinoids), while, in severe cases, systemic, classical or biological therapies are usually required ( Several therapies targeting immunometabolism exist, including pharmacological agents with known anti-inflammatory properties that target metabolism, such as metformin, dimethyl fumarate and methotrexate, reviewed by 5.1 Glycolysis A promising metabolic target of psoriasis is the dependence of activated keratinocytes and T cells on glucose and the upregulation of the Glut1 transporter

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