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It has been shown that once activated, plasmin activates matrix metalloproteinases that allows for macrophage movement through the extracellular matrix [94]

More recent studies show that zinc, at low concentrations (512.5 M), activates NADPH oxidase via PKC, leading to superoxide radical production
The switch from an immunologically centered pathogenetic hypothesis to a metabolic-based theory would represent a groundbreaking change in the setting of vitiligo for its therapeutic implications

Muntaner-Mas A, Palou P, Vidal-Conti J et al (2018) A mediation analysis on the relationship of physical fitness components, obesity, and academic performance in children
