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Description
Injectable delivery bypasses digestion and provides more direct systemic exposure

This selectivity limitation may be especially relevant for repurposing inhibitors of other proteases for 3CL protease or applying compounds with covalent warheads designed to target cysteine proteases

In astrocytes, glutamate is transformed into glutamine, which is safely transported back to neurons

nPKC activation internalizes selectively Mrp2

10.3389/fbioe.2021.767641 63 LiaoL.SuX.YangX.HuC.LiB.LvY.et al (2016)
